Generation and Characterization of Siglec-F-Specific Monoclonal Antibodies

Generation and Characterization of Siglec-F-Specific Monoclonal Antibodies

Siglec-F (SF) is a surface glycoprotein expressed by mouse eosinophils and induces caspase- and mitochondria-dependent apoptosis after engagement with its cognate ligand or specific antibodies. This targeting eosinophils by monoclonal antibodies may help diverse diseases associated with increased fr...

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Bibliographic Details
Main Authors: Sima Shahmohammadi-Farid, Roya Ghods, Mahmood Jeddi-Tehrani, Ali-Ahmad Bayat, Nazanin Mojtabavi, Alireza Razavi, Amir-Hassan Zarnani
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2017-12-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Epitopes
Flow cytometry
Monoclonal antibody
Native protein
Siglec-F
Western blotting
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/1306

Internet

https://ijaai.tums.ac.ir/index.php/ijaai/article/view/1306

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