Generation and Characterization of Siglec-F-Specific Monoclonal Antibodies

Siglec-F (SF) is a surface glycoprotein expressed by mouse eosinophils and induces caspase- and mitochondria-dependent apoptosis after engagement with its cognate ligand or specific antibodies. This targeting eosinophils by monoclonal antibodies may help diverse diseases associated with increased fr...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Sima Shahmohammadi-Farid, Roya Ghods, Mahmood Jeddi-Tehrani, Ali-Ahmad Bayat, Nazanin Mojtabavi, Alireza Razavi, Amir-Hassan Zarnani
Format: Artikel
Sprache:English
Veröffentlicht: Tehran University of Medical Sciences 2017-12-01
Schriftenreihe:Iranian Journal of Allergy, Asthma and Immunology
Schlagworte:
Online Zugang:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/1306