Obesity-Associated Metabolic Disturbances Reverse the Antioxidant and Anti-Inflammatory Properties of High-Density Lipoproteins in Microglial Cells

Obesity-Associated Metabolic Disturbances Reverse the Antioxidant and Anti-Inflammatory Properties of High-Density Lipoproteins in Microglial Cells

High-density lipoproteins (HDLs) play an important role in reverse cholesterol transport and present antioxidant properties, among others. In the central nervous system (CNS), there are HDLs, where these lipoproteins could influence brain health. Owing to the new evidence of HDL functionality remode...

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Bibliographic Details
Main Authors: Elena Grao-Cruces, Maria C. Millan-Linares, Maria E. Martin-Rubio, Rocio Toscano, Sergio Barrientos-Trigo, Beatriz Bermudez, Sergio Montserrat-de la Paz
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Biomedicines
Subjects:
obesity
paraoxonase
lipoproteins
oxidation
microglia
neuroinflammation
Online Access:https://www.mdpi.com/2227-9059/9/11/1722

Internet

https://www.mdpi.com/2227-9059/9/11/1722

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