MBOAT7 down-regulation by genetic and environmental factors predisposes to MAFLD

Metabolic associated fatty liver disease (MAFLD) encompasses a broad spectrum of hepatic disorders, which include steatosis, nonalcoholic steatohepatitis (NASH), fibrosis and cirrhosis, that is a critical risk factor for hepatocellular carcinoma (HCC) development. Its pathogenesis is intertwined wit...

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Bibliographic Details
Main Authors: Marica Meroni, Miriam Longo, Anna L. Fracanzani, Paola Dongiovanni
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420302413