Insights on Ultrafiltration-Based Separation for the Purification and Quantification of Methotrexate in Nanocarriers

Insights on Ultrafiltration-Based Separation for the Purification and Quantification of Methotrexate in Nanocarriers

The evaluation of encapsulation efficiency is a regulatory requirement for the characterization of drug delivery systems. However, the difficulties in efficiently separating nanomedicines from the free drug may compromise the achievement of accurate determinations. Herein, ultrafiltration was exploi...

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Bibliographic Details
Main Authors: Sara S. Marques, Inês I. Ramos, Sara R. Fernandes, Luisa Barreiros, Sofia A. C. Lima, Salette Reis, M. Rosário M. Domingues, Marcela A. Segundo
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Molecules
Subjects:
drug delivery
encapsulation efficiency
permeation
separative methods
ultrafiltration
Online Access:https://www.mdpi.com/1420-3049/25/8/1879

Internet

https://www.mdpi.com/1420-3049/25/8/1879

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