Human Leukocyte Antigens class II (HLA II) gene profile from an admixed population of patients with type 1 diabetes with severe diabetic retinopathy: a nested case-control study in Brazil

Abstract Background Although the well-established role of the HLA genes on the predisposition of type 1 diabetes (T1D), its contribution to the development and progression of diabetic retinopathy is still unclear, especially in admixed populations. We aimed to study the relationship between HLA alle...

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Main Authors: Deborah Conte Santos, Luís Cristóvão Porto, Marcela Haas Pizarro, Laura Gomes Nunes de Melo, Dayse A. Silva, Romulo Vianna Oliveira, Anna Paula Villela, Luiza Harcar Muniz, Camila Soares, Lucianne Righeti Monteiro Tannus, Karla Rezende Guerra Drummond, André Araújo Pinheiro, Felipe Mallmann, Franz Schubert Lopes Leal, Fernando Korn Malerbi, Paulo Henrique Morales, Marília Brito Gomes
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Online Access:https://doi.org/10.1186/s13098-021-00702-y