Saliva enhances infection of gingival fibroblasts by herpes simplex virus 1.

Oral herpes is a highly prevalent infection caused by herpes simplex virus 1 (HSV-1). After an initial infection of the oral cavity, HSV-1 remains latent in sensory neurons of the trigeminal ganglia. Episodic reactivation of the virus leads to the formation of mucocutaneous lesions (cold sores), but...

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Bibliographic Details
Main Authors: Yi Zuo, J Charles Whitbeck, Gabriel J Haila, Abraham A Hakim, Paul W Rothlauf, Roselyn J Eisenberg, Gary H Cohen, Claude Krummenacher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0223299