Variance heterogeneity analysis for detection of potentially interacting genetic loci: method and its limitations

<p>Abstract</p> <p>Background</p> <p>Presence of interaction between a genotype and certain factor in determination of a trait's value, it is expected that the trait's variance is increased in the group of subjects having this genotype. Thus, test of heterogen...

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Bibliographic Details
Main Authors: van Duijn Cornelia, Witteman Jacqueline CM, Dehghan Abbas, Struchalin Maksim V, Aulchenko Yurii S
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Genetics
Online Access:http://www.biomedcentral.com/1471-2156/11/92