Tocilizumab may slow radiographic progression in patients with systemic or polyarticular-course juvenile idiopathic arthritis: post hoc radiographic analysis from two randomized controlled trials

Abstract Background Few clinical trials have investigated the prevention of radiographic progression in children with juvenile idiopathic arthritis treated with antirheumatic drugs. This study aimed to investigate radiographic progression in patients with systemic juvenile idiopathic arthritis (sJIA...

Full description

Bibliographic Details
Main Authors: Clara Malattia, Nicolino Ruperto, Silvia Pederzoli, Elena Palmisani, Angela Pistorio, Carine Wouters, Pavla Dolezalova, Berit Flato, Stella Garay, Gabriella Giancane, Chris Wells, Wendy Douglass, Hermine I. Brunner, Fabrizio De Benedetti, Angelo Ravelli, for the Paediatric Rheumatology International Trials Organisation (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG)
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Arthritis Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13075-020-02303-y