Effects of telmisartan and olmesartan on insulin sensitivity and renal function in spontaneously hypertensive rats fed a high fat diet
Although telmisartan, an angiotensin II receptor blocker (ARB), has an agonistic action for proliferator-activated receptor (PPAR)-γ in vitro, it remains to be determined whether telmisartan exerts such an action in vivo using a non-toxic dose (<5 mg/kg in rats). To address the issue, telmisartan...
Main Authors: | Hayato Yanagihara, Kentaro Ushijima, Yusuke Arakawa, Ken-ichi Aizawa, Akio Fujimura |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-07-01
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Series: | Journal of Pharmacological Sciences |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861316300731 |
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