Synthesis of a Novel Tetracyclic Isoxazole by Intramolecular Nitrile Oxide Cycloaddition

Intramolecular cycloadditions have the great advantage of forming two rings simultaneously. We report the use of intramolecular [3 + 2] cycloaddition of the nitrile oxide derived from an <i>N</i>-propargylbenzimidazole oxime in the synthesis of a hitherto unreported tetracyclic isoxazole...

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Bibliographic Details
Main Authors: Gavin R. Hoffman, Allen M. Schoffstall
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Molbank
Subjects:
Online Access:https://www.mdpi.com/1422-8599/2024/1/M1767