Acquired Uniparental Disomy Regions Are Associated with Disease Outcome in Patients with Oral Cavity and Oropharynx But Not Larynx Cancers

Acquired uniparental disomy (aUPD) regions pinpoint homozygousity and monoallelic expressed genes. We analyzed The Cancer Genome Atlas single-nucleotide polymorphism arrays and expression data from oral cavity, oropharynx, and larynx cancers to identify frequency of aUPD in each tumor type and assoc...

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Bibliographic Details
Main Authors: Musaffe Tuna, Christopher I. Amos, Gordon B. Mills
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523319305625