Identification of pivotal genes and regulatory networks associated with atherosclerotic carotid artery stenosis based on comprehensive bioinformatics analysis and machine learning

Objective:Bioinformatics methods were applied to investigate the pivotal genes and regulatory networks associated with atherosclerotic carotid artery stenosis (ACAS) and provide new insights for the treatment of this disease.Methods:The study utilized five ACAS datasets (GSE100927, GSE11782, GESE288...

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Bibliographic Details
Main Authors: Xiaohong Qin, Rui Ding, Haoran Lu, Wenfei Zhang, Shanshan Wei, Baowei Ji, Rongxin Geng, Liquan Wu, Zhibiao Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1364160/full