Deletion of TRIB3 disrupts the tumor progression induced by integrin αvβ3 in lung cancer

Abstract Background Integrin αvβ3 has been proposed as crucial determinant for tumor sustained progression and a molecular marker for the estimation of tumor angiogenesis. Our study suggested that integrin αvβ3 could efficiently promote lung cancer cell proliferation and stem-like phenotypes in a tr...

Full description

Bibliographic Details
Main Authors: Wen Zhou, Junjun Ma, Lifeng Meng, Dabei Liu, Jun Chen
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-022-09593-2