Central Injection of Substance P Antagonizes the RF Amide-Related Peptide-3 Impacts on Hypothalamic KISS-1 and GnRH Gene Expressions in Male Wistar Rats
Introduction: Gonadotropin-inhibitory hormone (GnIH) and its mammalian orthologue RF amide-related peptide (RFRP) are known to inhibit the secretion of gonadotropins. In addition, substance P (SP), a member of tachykinin’s family, can increase the firing rate of kisspeptin/ neurokinin B/dynorphin (K...
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| Format: | Article |
| Language: | English |
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Zabol University of Medical sciences
2018-09-01
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| Series: | International Journal of Basic Science in Medicine |
| Subjects: | |
| Online Access: | http://ijbsm.zbmu.ac.ir/PDF/ijbsm-3254 |