Lethal severe fever with thrombocytopenia syndrome virus infection causes systemic germinal centre failure and massive T cell apoptosis in cats

Lethal severe fever with thrombocytopenia syndrome virus infection causes systemic germinal centre failure and massive T cell apoptosis in cats

IntroductionSevere fever with thrombocytopenia syndrome (SFTS) is a fatal viral disease characterized by high fever, thrombocytopenia, leukopenia, and multi-organ haemorrhage. Disruption of the humoral immune response and decreased lymphocyte numbers are thought to contribute to the disease severity...

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Main Authors: Yusuke Sakai, Serina Mura, Yuko Kuwabara, Saya Kagimoto, Masashi Sakurai, Masahiro Morimoto, Eun-sil Park, Masayuki Shimojima, Noriyo Nagata, Yasushi Ami, Tomoki Yoshikawa, Naoko Iwata-Yoshikawa, Shuetsu Fukushi, Shumpei Watanabe, Takeshi Kurosu, Akiko Okutani, Masanobu Kimura, Koichi Imaoka, Masayuki Saijo, Shigeru Morikawa, Tadaki Suzuki, Ken Maeda
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Microbiology
Subjects:
severe fever with thrombocytopenia syndrome
cats
histopathology
lymph nodes
germinal centre reaction
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1333946/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2023.1333946/full

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