A scalable 3D tissue culture pipeline to enable functional therapeutic screening for pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease targeting the alveolar gas exchange apparatus, leading to death by asphyxiation. IPF progresses on a tissue scale through aberrant matrix remodeling, enhanced cell contraction, and subsequent microenvironment densification. Although two ph...

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Bibliographic Details
Main Authors: Katherine A. Cummins, Peter B. Bitterman, Daniel J. Tschumperlin, David K. Wood
Format: Article
Language:English
Published: AIP Publishing LLC 2021-12-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0054967