A scalable 3D tissue culture pipeline to enable functional therapeutic screening for pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease targeting the alveolar gas exchange apparatus, leading to death by asphyxiation. IPF progresses on a tissue scale through aberrant matrix remodeling, enhanced cell contraction, and subsequent microenvironment densification. Although two ph...
Main Authors: | Katherine A. Cummins, Peter B. Bitterman, Daniel J. Tschumperlin, David K. Wood |
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Format: | Article |
Language: | English |
Published: |
AIP Publishing LLC
2021-12-01
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Series: | APL Bioengineering |
Online Access: | http://dx.doi.org/10.1063/5.0054967 |
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