Mitophagy in carcinogenesis and cancer treatment

Abstract In order to maintain a functional mitochondrial network, cells have developed a quality control mechanism, namely mitophagy. This process can be induced through different pathways. The most studied is the so-called PINK1/Parkin pathway, which is associated with ubiquitylation of several mit...

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Bibliographic Details
Main Authors: Tatiana V. Denisenko, Vladimir Gogvadze, Boris Zhivotovsky
Format: Article
Language:English
Published: Springer 2021-12-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-021-00454-1