Affecting long-term fear memory formation through optical control of Rac1 GTPase and PAK activity in lateral amygdala

Abstract Fear conditioning, a behavioral model for studying fear-related disorders, is believed to be formed by alterations of synaptic efficacy mediated by changes in synaptic transmission and neuronal morphology in lateral amygdala (LA). Rac GTPase and its downstream effector p21-activated kinase...

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Bibliographic Details
Main Authors: Aniruddha Das, Monica Dines, Jessica M. Alapin, Raphael Lamprecht
Format: Article
Language:English
Published: Nature Portfolio 2017-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-13674-9