Affecting long-term fear memory formation through optical control of Rac1 GTPase and PAK activity in lateral amygdala
Abstract Fear conditioning, a behavioral model for studying fear-related disorders, is believed to be formed by alterations of synaptic efficacy mediated by changes in synaptic transmission and neuronal morphology in lateral amygdala (LA). Rac GTPase and its downstream effector p21-activated kinase...
Main Authors: | Aniruddha Das, Monica Dines, Jessica M. Alapin, Raphael Lamprecht |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-10-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-13674-9 |
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