Lipofuscin Hypothesis of Alzheimer’s Disease

The primary culprit responsible for Alzheimer’s disease (AD) remains unknown. Aβ protein has been identified as the main component of amyloid of senile plaques, the hallmark lesion of AD, but it is not definitively established whether the formation of extracellular Aβ deposits is the absolute harbin...

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Bibliographic Details
Main Authors: Giorgio Giaccone, Laura Orsi, Chiara Cupidi, Fabrizio Tagliavini
Format: Article
Language:English
Published: Karger Publishers 2011-09-01
Series:Dementia and Geriatric Cognitive Disorders Extra
Subjects:
Online Access:http://www.karger.com/Article/FullText/329544