Development of a data-driven approach to Adverse Outcome Pathway network generation: a case study on the EATS-modalities

Development of a data-driven approach to Adverse Outcome Pathway network generation: a case study on the EATS-modalities

Adverse Outcome Pathways (AOPs) summarize mechanistic understanding of toxicological effects and have, for example, been highlighted as a promising tool to integrate data from novel in vitro and in silico methods into chemical risk assessments. Networks based on AOPs are considered the functional im...

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Bibliographic Details
Main Authors: Linus Wiklund, Sara Caccia, Marek Pípal, Penny Nymark, Anna Beronius
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Toxicology
Subjects:
AOP
AOP network
EATS-modalities
endocrine disruptors
ED assessment
computational
Online Access:https://www.frontiersin.org/articles/10.3389/ftox.2023.1183824/full

Internet

https://www.frontiersin.org/articles/10.3389/ftox.2023.1183824/full

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