Advancements Exploring Major Depressive Disorder: Insights on Oxidative Stress, Serotonin Metabolism, BDNF, HPA Axis Dysfunction, and Pharmacotherapy Advances

Advancements Exploring Major Depressive Disorder: Insights on Oxidative Stress, Serotonin Metabolism, BDNF, HPA Axis Dysfunction, and Pharmacotherapy Advances

Major depressive disorder (MDD), a prevalent mental illness, is marked by a complex mixture of biological factors. This review focuses on the roles of oxidative stress, tryptophan-serotonin metabolism, brain-derived neurotrophic factor (BDNF), and the hypothalamic–pituitary–adrenal (HPA) axis in MDD...

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Bibliographic Details
Main Authors: Ana Salomé Correia, Nuno Vale
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Translational Medicine
Subjects:
major depressive disorder
oxidative stress
tryptophan
serotonin
brain-derived neurotrophic factor
hypothalamic–pituitary–adrenal axis
Online Access:https://www.mdpi.com/2673-8937/4/1/10

Internet

https://www.mdpi.com/2673-8937/4/1/10

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