The Role of PIM Kinases in Pediatric Solid Tumors

PIM kinases have been identified as potential therapeutic targets in several malignancies. Here, we provide an in-depth review of PIM kinases, including their structure, expression, activity, regulation, and role in pediatric carcinogenesis. Also included is a brief summary of the currently availabl...

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Bibliographic Details
Main Authors: Janet Rae Julson, Raoud Marayati, Elizabeth Ann Beierle, Laura Lee Stafman
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/15/3565