Longitudinal 16S rRNA Sequencing Reveals Relationships among Alterations of Gut Microbiota and Nonalcoholic Fatty Liver Disease Progression in Mice

Longitudinal 16S rRNA Sequencing Reveals Relationships among Alterations of Gut Microbiota and Nonalcoholic Fatty Liver Disease Progression in Mice

ABSTRACT Nonalcoholic fatty liver disease (NAFLD) is a prevalent and progressive disease spectrum ranging from nonalcoholic fatty liver (NAFL) to nonalcoholic steatohepatitis (NASH), yet there is no effective treatment and efficient noninvasive diagnostic method for NASH. The present study investiga...

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Bibliographic Details
Main Authors: Aoxiang Zhuge, Shengjie Li, Pengcheng Lou, Wenrui Wu, Kaiceng Wang, Yin Yuan, Jiafeng Xia, Bo Li, Lanjuan Li
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:Microbiology Spectrum
Subjects:
gut microbiota
NAFLD progression
Akkermansia muciniphila
fibrosis
bile acid metabolism
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00047-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.00047-22

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