Mutual-information based optimal experimental design for hyperpolarized $$^{13}$$ 13 C-pyruvate MRI
Abstract A key parameter of interest recovered from hyperpolarized (HP) MRI measurements is the apparent pyruvate-to-lactate exchange rate, $$k_{{\textrm PL}}$$ k P L , for measuring tumor metabolism. This manuscript presents an information-theory-based optimal experimental design approach that mini...
मुख्य लेखकों: | , , , , , , |
---|---|
स्वरूप: | लेख |
भाषा: | English |
प्रकाशित: |
Nature Portfolio
2023-10-01
|
श्रृंखला: | Scientific Reports |
ऑनलाइन पहुंच: | https://doi.org/10.1038/s41598-023-44958-y |