Mutual-information based optimal experimental design for hyperpolarized $$^{13}$$ 13 C-pyruvate MRI

Abstract A key parameter of interest recovered from hyperpolarized (HP) MRI measurements is the apparent pyruvate-to-lactate exchange rate, $$k_{{\textrm PL}}$$ k P L , for measuring tumor metabolism. This manuscript presents an information-theory-based optimal experimental design approach that mini...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Prashant K. Jha, Christopher Walker, Drew Mitchell, J. Tinsley Oden, Dawid Schellingerhout, James A. Bankson, David T. Fuentes
स्वरूप: लेख
भाषा:English
प्रकाशित: Nature Portfolio 2023-10-01
श्रृंखला:Scientific Reports
ऑनलाइन पहुंच:https://doi.org/10.1038/s41598-023-44958-y