Critical role of TLR activation in viral replication, persistence, and pathogenicity of Theiler’s virus

Critical role of TLR activation in viral replication, persistence, and pathogenicity of Theiler’s virus

Theiler’s murine encephalomyelitis virus (TMEV) establishes persistent viral infections in the central nervous system and induces chronic inflammatory demyelinating disease in susceptible mice. TMEV infects dendritic cells, macrophages, B cells, and glial cells. The state of TLR activation in the ho...

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Bibliographic Details
Main Author: Byung S. Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
TLRs
chronic viral infection
inflammation
apoptosis
autoimmunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1167972/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1167972/full

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