HIV-1 Gag, Pol, and Env diversified with limited adaptation since the 1980s

HIV-1 Gag, Pol, and Env diversified with limited adaptation since the 1980s

ABSTRACTKnowledge of HIV-1 global sequence diversity is critical for developing an effective prophylactic against HIV-1 infection. We developed the Hervé platform to analyze and visualize trends in HIV-1 diversification. Using Hervé, we analyzed 4,830 Env, 4,407 Gag, and 3,002 Pol publicly available...

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Bibliographic Details
Main Authors: Eric Lewitus, Yifan Li, Hongjun Bai, Phuc Pham, Morgane Rolland
Format: Article
Language:English
Published: American Society for Microbiology 2024-03-01
Series:mBio
Subjects:
HIV-1
evolution
diversity
Online Access:https://journals.asm.org/doi/10.1128/mbio.01749-23

Internet

https://journals.asm.org/doi/10.1128/mbio.01749-23

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