Synthesis, Half-Wave Potentials and Antiproliferative Activity of 1-Aryl-substituted Aminoisoquinolinequinones

Synthesis, Half-Wave Potentials and Antiproliferative Activity of 1-Aryl-substituted Aminoisoquinolinequinones

The synthesis of a variety of 1-aryl-7-phenylaminoisoquinolinequinones from 1,4-benzoquinone and arylaldehydes via the respective 1-arylisoquinolinequinones is reported. The cyclic voltammograms of the new compounds exhibit two one-electron reduction waves to the corresponding radical-anion and dia...

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Bibliographic Details
Main Authors: Juana Andrea Ibacache, Virginia Delgado, Julio Benites, Cristina Theoduloz, Verónica Arancibia, Giulio G. Muccioli, Jaime A. Valderrama
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:Molecules
Subjects:
isoquinolinequinones
enaminones
half-wave potential
antiproliferative activity
SAR analysis
Online Access:http://www.mdpi.com/1420-3049/19/1/726

Internet

http://www.mdpi.com/1420-3049/19/1/726

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