A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age‐dependent differences in absorption

A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age‐dependent differences in absorption

Abstract Little is known about the impact of age on the processes governing human intestinal drug absorption. The Ussing chamber is a system to study drug transport across tissue barriers, but it has not been used to study drug absorption processes in children. This study aimed to explore the feasib...

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Bibliographic Details
Main Authors: Eva J. Streekstra, Márton Kiss, Jeroen van denHeuvel, Johan Nicolaï, Petra van denBroek, Sanne M. B. I. Botden, Martijn W. J. Stommel, Lara vanRijssel, Anna‐Lena Ungell, Evita van deSteeg, Frans G. M. Russel, Saskia N. deWildt
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.13368

Internet

https://doi.org/10.1111/cts.13368

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