TSP50 Attenuates DSS‐Induced Colitis by Regulating TGF‐β Signaling Mediated Maintenance of Intestinal Mucosal Barrier Integrity

TSP50 Attenuates DSS‐Induced Colitis by Regulating TGF‐β Signaling Mediated Maintenance of Intestinal Mucosal Barrier Integrity

Abstract The integrity of the intestinal mucosal barrier is crucial for protecting the intestinal epithelium against invasion by commensal bacteria and pathogens, thereby combating colitis. The investigation revealed that the absence of TSP50 compromised the integrity of the intestinal mucosal barri...

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Bibliographic Details
Main Authors: Jiawei Li, Chunxue Niu, Huihan Ai, Xiaoli Li, Linlin Zhang, Yan Lang, Shuyue Wang, Feng Gao, Xianglin Mei, Chunlei Yu, Luguo Sun, Yanxin Huang, Lihua Zheng, Guannan Wang, Ying Sun, Xiaoguang Yang, Zhenbo Song, Yongli Bao
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Advanced Science
Subjects:
IBD
intestinal barrier
TGF‐Î2
TSP50
Online Access:https://doi.org/10.1002/advs.202305893

Internet

https://doi.org/10.1002/advs.202305893

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