De novo polymerase activity and oligomerization of hepatitis C virus RNA-dependent RNA-polymerases from genotypes 1 to 5.

De novo polymerase activity and oligomerization of hepatitis C virus RNA-dependent RNA-polymerases from genotypes 1 to 5.

Hepatitis C virus (HCV) shows a great geographical diversity reflected in the high number of circulating genotypes and subtypes. The response to HCV treatment is genotype specific, with the predominant genotype 1 showing the lowest rate of sustained virological response. Virally encoded enzymes are...

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Bibliographic Details
Main Authors: Pilar Clemente-Casares, Alberto J López-Jiménez, Itxaso Bellón-Echeverría, José Antonio Encinar, Elisa Martínez-Alfaro, Ricardo Pérez-Flores, Antonio Mas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21490973/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21490973/?tool=EBI

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