Bioconjugation of a Collagen-Mimicking Peptide Onto Poly(vinyl alcohol) Encourages Endothelialization While Minimizing Thrombosis

Bioconjugation of a Collagen-Mimicking Peptide Onto Poly(vinyl alcohol) Encourages Endothelialization While Minimizing Thrombosis

Poly(vinyl alcohol) hydrogel, PVA, is a suitable material for small-diameter vascular grafting. However, the bioinert properties of the material do not allow for in situ endothelialization, which is needed to combat common graft failure mechanisms, such as intimal hyperplasia and thrombosis. In this...

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Bibliographic Details
Main Authors: Novella M. Bates, Heather E. Heidenreich, Meghan E. Fallon, Yuan Yao, Evelyn K. F. Yim, Monica T. Hinds, Deirdre E. J. Anderson
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
poly(vinyl alcohol)
GFPGER
carbonyldiimidazole
hemocompatibility
vascular graft
platelets
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2020.621768/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2020.621768/full

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