Stable Pom1 clusters form a glucose-modulated concentration gradient that regulates mitotic entry

Control of cell size requires molecular size sensors that are coupled to the cell cycle. Rod-shaped fission yeast cells divide at a threshold size partly due to Cdr2 kinase, which forms nodes at the medial cell cortex where it inhibits the Cdk1-inhibitor Wee1. Pom1 kinase phosphorylates and inhibits...

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Bibliographic Details
Main Authors: Corey A H Allard, Hannah E Opalko, James B Moseley
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/46003