Novel Steroidal[17,16-<i>d</i>]pyrimidines Derived from Epiandrosterone and Androsterone: Synthesis, Characterization and Configuration-Activity Relationships

Two series of novel steroidal[17,16-<i>d</i>]pyrimidines derived from natural epiandrosterone and androsterone were designed and synthesized, and these compounds were screened for their potential anticancer activities. The preliminary bioassay indicated that some of these prepared compou...

Full description

Bibliographic Details
Main Authors: Fei Yang, Fang Liu, Yong Min, Liqiao Shi, Manli Liu, Kaimei Wang, Shaoyong Ke, Yan Gong, Ziwen Yang
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/6/2691