Bisphenol A impairs hepatic glucose sensing in C57BL/6 male mice.

Glucose sensing (eg. glucokinase activity) becomes impaired in the development of type 2 diabetes, the etiology of which is unclear. Estrogen can stimulate glucokinase activity, whereas the pervasive environmental pollutant bisphenol A (BPA) can inhibit estrogen action, hence we aimed to determine t...

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Bibliographic Details
Main Authors: Leigh Perreault, Carrie McCurdy, Anna A Kerege, Julie Houck, Kristine Færch, Bryan C Bergman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3726717?pdf=render