The molecular pathogenesis of multiple myeloma

Multiple myeloma (MM) is characterized by uncontrolled proliferation and accumulation of clonal plasma cells within the bone marrow. However, the cell of origin is a B-lymphocyte acquiring aberrant genomic events in the germinal center of a lymph node as off-target events during somatic-hypermutatio...

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Bibliographic Details
Main Authors: Niccolò Bolli, Giovanni Martinelli, Claudio Cerchione
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Hematology Reports
Subjects:
Online Access:https://www.pagepress.org/journals/index.php/hr/article/view/9054