Legionella pneumophila Carbonic Anhydrases: Underexplored Antibacterial Drug Targets

Carbonic anhydrases (CAs, EC 4.2.1.1) are metalloenzymes which catalyze the hydration of carbon dioxide to bicarbonate and protons. Many pathogenic bacteria encode such enzymes belonging to the α-, β-, and/or γ-CA families. In the last decade, enzymes from some of these pathogens, including Legionel...

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Bibliographic Details
Main Author: Claudiu T. Supuran
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Pathogens
Subjects:
Online Access:http://www.mdpi.com/2076-0817/5/2/44