High-grade transformation of a polymorphous adenocarcinoma of the salivary gland: a case report and review of the literature

High-grade transformation of a polymorphous adenocarcinoma of the salivary gland: a case report and review of the literature

BackgroundPolymorphous adenocarcinoma (PAC) represents the second most widespread neoplasm of the minor salivary glands. These tumors rarely develop a histological progression from low-grade to high-grade malignancy, named “high-grade transformation” (HGT). Only nine cases are described in literatur...

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Main Authors: Giacomo Miserocchi, Massimo Bassi, Giovanni De Luca, Sebastiano Calpona, Francesco De Rosa, Alberto Bongiovanni, Elisabetta Parisi, Giandomenico Di Menna, Alessandro De Vita, Chiara Liverani, Chiara Spadazzi, Claudia Cocchi, Silvia Vanni, Laura Capelli, Massimo Magnani, Giuseppe Meccariello, Claudio Vicini, Angelo Campobassi, Laura Mercatali, Toni Ibrahim
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Oncology
Subjects:
polymorphous adenocarcinoma
high-grade transformation
minor salivary gland
gene expression profiling
oral floor
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1245043/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1245043/full

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