Comparative analysis of basal and etoposide-induced alterations in gene expression by DNA-PKcs kinase activity

Comparative analysis of basal and etoposide-induced alterations in gene expression by DNA-PKcs kinase activity

Background: Maintenance of the genome is essential for cell survival, and impairment of the DNA damage response is associated with multiple pathologies including cancer and neurological abnormalities. DNA-PKcs is a DNA repair protein and a core component of the classical nonhomologous end-joining pa...

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Bibliographic Details
Main Authors: Sk Imran Ali, Mohammad J. Najaf-Panah, Kennedi B. Pyper, F. Ester Lujan, Johnny Sena, Amanda K. Ashley
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Genetics
Subjects:
DNA-PKcs
DNA damage repair
non-homologous end-joining
etoposide
gene expression
transcriptome
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1276365/full

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https://www.frontiersin.org/articles/10.3389/fgene.2024.1276365/full

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