Excitation-Dependent pKa Extends the Sensing Range of Fluorescence Lifetime pH Sensors

Biological activity is strongly dependent on pH, which fluctuates within a variety of neutral, alkaline, and acidic local environments. The heterogeneity of tissue and subcellular pH has driven the development of sensors with different pKa values, and a huge assortment of fluorescent sensors have be...

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Bibliographic Details
Main Authors: Emily P. Haynes, Mary Canzano, Mathew Tantama
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/24/23/7531