Rationale and design of Tenecteplase Reperfusion Therapy in Acute Ischaemic Cerebrovascular Events III (TRACE III): a randomised, phase III, open-label, controlled trial

Background and purpose Recombinant human TNK tissue-type plasminogen activator (rhTNK-tPA) was not inferior to alteplase for ischaemic stroke within 4.5 hours. Our study aimed to investigate the efficacy and safety of rhTNK-tPA in patients who had an ischaemic stroke due to large vessel occlusion (L...

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Bibliographic Details
Main Authors: Bruce C V Campbell, Yongjun Wang, Xingquan Zhao, Yunyun Xiong, Hao Li, Xia Meng, Yuesong Pan, Lee H Schwamm, Mark Parsons, Marc Fisher
Format: Article
Language:English
Published: BMJ Publishing Group
Series:Stroke and Vascular Neurology
Online Access:https://svn.bmj.com/content/early/2023/05/29/svn-2023-002310.full