Identifying PLAUR as a Pivotal Gene of Tumor Microenvironment and Regulating Mesenchymal Phenotype of Glioblastoma

Identifying PLAUR as a Pivotal Gene of Tumor Microenvironment and Regulating Mesenchymal Phenotype of Glioblastoma

The mesenchymal (MES) phenotype of glioblastoma (GBM) is the most aggressive and therapy-resistant subtype of GBM. The MES phenotype transition during tumor progression results from both tumor-intrinsic genetic alterations and tumor-extrinsic microenvironmental factors. In this study, we sought to i...

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Bibliographic Details
Main Authors: Zaixiang Fu, Zihang Chen, Jingya Ye, Jianxiong Ji, Weifang Ni, Weibo Lin, Haopu Lin, Liquan Lu, Ganggui Zhu, Qin Xie, Feng Yan, Gao Chen, Fuyi Liu
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cancers
Subjects:
glioblastoma
PLAUR
tumor microenvironment
mesenchymal phenotype
single-cell RNA sequencing
Online Access:https://www.mdpi.com/2072-6694/16/4/840

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https://www.mdpi.com/2072-6694/16/4/840

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