Early truncation of the N‐terminal variable region of EYA4 gene causes dominant hearing loss without cardiac phenotype

Early truncation of the N‐terminal variable region of EYA4 gene causes dominant hearing loss without cardiac phenotype

Abstract Background Autosomal dominant hearing loss (ADHL) accounts for about 20% of all hereditary non‐syndromic HL. Truncating mutations of the EYA4 gene can cause either non‐syndromic ADHL or syndromic ADHL with cardiac abnormalities. It has been proposed that truncations of the C‐terminal Eya do...

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Bibliographic Details
Main Authors: Yanfang Mi, Danhua Liu, Beiping Zeng, Yongan Tian, Hui Zhang, Bei Chen, Juanli Zhang, Hong Xue, Wenxue Tang, Yulin Zhao, Hongen Xu
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
autosomal dominant hearing loss
EYA4
next‐generation sequencing
Online Access:https://doi.org/10.1002/mgg3.1569

Internet

https://doi.org/10.1002/mgg3.1569

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