Steroid receptor coactivator-3 inhibition generates breast cancer antitumor immune microenvironment

Steroid receptor coactivator-3 inhibition generates breast cancer antitumor immune microenvironment

Abstract Background The tumor immune microenvironment (TIME) generated by cancer-infiltrating immune cells has a crucial role in promoting or suppressing breast cancer progression. However, whether the steroid receptor coactivator-3 (SRC-3) modulates TIME to progress breast cancer is unclear. Theref...

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Bibliographic Details
Main Authors: Sang Jun Han, Nuri Sung, Jin Wang, Bert W. O’Malley, David M. Lonard
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Breast Cancer Research
Subjects:
Steroid receptor coactivator inhibitor
Antitumor immunity
Breast cancer
E0771 cells
Interleukin 1 receptor antagonist
C-X-C motif chemokine ligand 9
Online Access:https://doi.org/10.1186/s13058-022-01568-2

Internet

https://doi.org/10.1186/s13058-022-01568-2

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