Xyloketal B Exhibits Its Antioxidant Activity through Induction of HO-1 in Vascular Endothelial Cells and Zebrafish

Xyloketal B Exhibits Its Antioxidant Activity through Induction of HO-1 in Vascular Endothelial Cells and Zebrafish

We previously reported that a novel marine compound, xyloketal B, has strong antioxidative actions in different models of cardiovascular diseases. Induction of heme oxygenase-1 (HO-1), an important endogenous antioxidant enzyme, has been considered as a potential therapeutic strategy for cardiovascu...

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Bibliographic Details
Main Authors: Guan-Lei Wang, Xi-Lin Lu, Zhong Pei, Yong-Cheng Lin, Ji-Yan Pang, Huan-Xing Su, Jie Liu, Yun-Ying Huang, Jie Li, Li-Yan Zhao, Jian-Wen Chen, Feng Yuan, Yong-Yuan Guan, Zhen-Xing Li
Format: Article
Language:English
Published: MDPI AG 2013-02-01
Series:Marine Drugs
Subjects:
xyloketal B
apoptosis
reactive oxygen species
HO-1
Nrf-2
Online Access:http://www.mdpi.com/1660-3397/11/2/504

Internet

http://www.mdpi.com/1660-3397/11/2/504

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