Differential lung gene expression changes in C57BL/6 and DBA/2 mice carrying an identical functional Mx1 gene reveals crucial differences in the host response

Differential lung gene expression changes in C57BL/6 and DBA/2 mice carrying an identical functional Mx1 gene reveals crucial differences in the host response

Abstract Background Influenza virus infections represent a major global health problem. The dynamin-like GTPase MX1 is an interferon-dependent antiviral host protein that confers resistance to influenza virus infections. Infection models in mice are an important experimental system to understand the...

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Bibliographic Details
Main Authors: Silke Bergmann, Linda Brunotte, Klaus Schughart
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Genomic Data
Subjects:
Influenza
Mouse
C57BL/6J
DBA/2J
MX1
Transcriptome
Online Access:https://doi.org/10.1186/s12863-024-01203-3

Internet

https://doi.org/10.1186/s12863-024-01203-3

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