Prostate cancer induced bone pain: pathobiology, current treatments and pain responses from recent clinical trials

Abstract Purpose Metastatic spread of prostate cancer to the skeleton may result in debilitating bone pain. In this review, we address mechanisms underpinning the pathobiology of metastatic prostate cancer induced bone pain (PCIBP) that include sensitization and sprouting of primary afferent sensory...

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Bibliographic Details
Main Authors: A. E. Smith, A. Muralidharan, M. T. Smith
Format: Article
Language:English
Published: Springer 2022-10-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-022-00569-z