Characterization of Antibodies against Receptor Activity-Modifying Protein 1 (RAMP1): A Cautionary Tale

Characterization of Antibodies against Receptor Activity-Modifying Protein 1 (RAMP1): A Cautionary Tale

Calcitonin gene-related peptide (CGRP) is a key component of migraine pathophysiology, yielding effective migraine therapeutics. CGRP receptors contain a core accessory protein subunit: receptor activity-modifying protein 1 (RAMP1). Understanding of RAMP1 expression is incomplete, partly due to the...

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Bibliographic Details
Main Authors: Erica R. Hendrikse, Tayla A. Rees, Zoe Tasma, Michael L. Garelja, Andrew Siow, Paul W. R. Harris, John B. Pawlak, Kathleen M. Caron, Elizabeth S. Blakeney, Andrew F. Russo, Levi P. Sowers, Thomas A. Lutz, Christelle Le Foll, Christopher S. Walker, Debbie L. Hay
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
RAMP1
brain
CGRP
migraine
amylin
GPCR
Online Access:https://www.mdpi.com/1422-0067/23/24/16035

Internet

https://www.mdpi.com/1422-0067/23/24/16035

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